Ace the NCLEX 2025 – Hit the Books and Nail That Nursing Badge!

Question: 1 / 400

Tissue plasminogen activator (tPA) to dissolve blood clots must be given within how many hours from onset of symptoms?

1 to 2 hours

The correct answer is that tissue plasminogen activator (tPA) should be administered within 3 to 4.5 hours from the onset of symptoms for it to be effective in dissolving blood clots, particularly in cases of acute ischemic stroke. This time frame is critical because the earlier tPA is given, the better the outcomes in terms of reducing morbidity and mortality associated with strokes. Administering it outside this time frame can increase the risk of serious complications, such as hemorrhage, especially if given too late.

While the first option suggests a shorter window, it does not align with the established guidelines for administering tPA. For professionals in the healthcare field and nurses preparing for the NCLEX, being aware of the guidelines and time-sensitive nature of administering tPA is essential for patient safety and optimal treatment outcomes.

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2 to 3 hours

3 to 4.5 hours

5 to 6 hours

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